Is thioridazine retinopathy progressive? Relationship of pigmentary changes to visual function.
نویسندگان
چکیده
منابع مشابه
Is thioridazine retinopathy progressive? Relationship of pigmentary changes to visual function.
Thioridazine toxicity has been described as a 'progressive chorioretinopathy', but this designation can be misleading. During the first year after thioridazine exposure retinal pigmentation evolves from a granular to a patchy or nummular appearance. However, visual function and the electroretinogram typically improve during this period. Some cases may show chorioretinal atrophy and functional l...
متن کاملThioridazine (Melleril) retinopathy.
The drug thioridazine was first introduced in I959 and Weekley, PQtts, Reboton, and May (I960) reported the first cases of pigmentary retinopathy, in four patients who had been given approximately 2 g. daily for 30-50 days. The manufacturers (Sandoz) subsequently recommended that a daily dose of 8oo mg. should not be exceeded and since then only about half a dozen articles have appeared (all in...
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The rare association of external ophthalmoplegia and ptosis with pigmentary degeneration of the retina was first described by Barnard and Scholz (I954) in a report of four cases. The subsequent literature was reviewed by Davidson (i960), 'who found that only eighteen cases had been described, and added one further case. Within this series he was able to define a relatively homogenous group of t...
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ژورنال
عنوان ژورنال: British Journal of Ophthalmology
سال: 1990
ISSN: 0007-1161
DOI: 10.1136/bjo.74.12.739